Cannabidiol, or CBD, is a popular natural remedy for a variety of health problems. It’s one of more than 100 chemical compounds called cannabinoids that are present in the cannabis plant, Cannabis sativa.
Tetrahydrocannabinol (THC) is the primary psychoactive cannabinoid found in cannabis, which implies it produces the euphoric sensation that is frequently associated with marijuana. CBD, on the other hand, is non-psychoactive.
CBD has a high level of concentration, which makes it an appealing choice for individuals seeking pain and other symptoms relief without the mind-altering effects of cannabis or other adverse side effects from pharmaceutical medicines.
CBD oil is a liquid that’s extracted from the cannabis plant and then mixed with a carrier oil like coconut oil or hemp seed oil. CBD can be found in a variety of items online and at stores, including dietary supplements, baths, beverages, and food.
This post covers six scientific health advantages of CBD, as well as potential negative effects and safety concerns associated with CBD products.
If you’re interested in learning more about CBD oil, be sure to read our other blog.
Since at least 2900 B.C., cannabis has been used to treat pain. More recently, scientists have identified that several components of cannabis, including CBD, contribute to its pain-relieving qualities.
The endocannabinoid system, which is found in the body’s central nervous system and peripheral nerves, controls a variety of activities such as sleep, hunger, pain sensation, and immune response.
The body generates endocannabinoids, neurotransmitters that bind to cannabinoid receptors in the brain.
CBD may help reduce chronic pain by influencing endocannabinoid receptor activity, reducing inflammation, and interacting with neurotransmitters, according to studies.
CBD, when taken alone, has been found to help with certain types of pain, such as nerve and back pain. However, it appears to work best when combined with THC.
A combination of CBD and THC has been found to be useful in treating pain associated with multiple sclerosis (MS) and arthritis in several human trials.
Still, there was no control group in the study, so placebo effects cannot be ruled out. According to one analysis, Sativex may help with MS-related neuropathic pain and chronic severe neuropathic pain. Sativex was also found to aid in the relief of anxiety and stress, which are significant contributors to chronic pain.
CBD also appears to help with the symptoms of rheumatoid arthritis, according to some research.
CBD, according to preclinical evidence from animal studies, has anti-inflammatory and analgesic effects relevant to arthritis, but human research is lacking. Although researchers are optimistic that CBD may be beneficial in the management of some types of pain, particularly when combined with THC, more high-quality research is needed to determine its efficacy in pain relief.
Anxiety disorders and other mental health problems may have a major influence on one’s general health and happiness.
Pharmaceutical medicines are frequently used to treat mental health issues, which can result in a variety of adverse effects, including drowsiness, agitation, sleeplessness, sexual dysfunction, and headaches. Furthermore, medications such as benzodiazepines have the potential for dependence and might lead to substance use disorder.
Many individuals living with anxiety disorders, for example, have become interested in this natural approach since it has shown promise as a therapy for several mental health issues including anxiety.
In a study of 57 guys published in the journal Psychopharmacology, those who took oral CBD 90 minutes before performing a simulated public speaking task received either treatment or a placebo. The 300-mg dosage of CBD was most effective at mitigating anxiety, according to the researchers.
CBD oil has been proved to be effective for treating insomnia and anxiety in children with post-traumatic stress disorder (PTSD), a type of anxiety illness. In adults, CBD was found to be helpful in reducing PTSD-related symptoms including nightmares.
CBD has also been found to aid in the treatment of social anxiety and other anxiety-related problems in a variety of studies. Even though some individuals claim that CBD alleviates depressive symptoms, evidence of CBD’s potential antidepressant capabilities is currently limited. However, several research suggest that it may help reduce depressive symptoms in persons with cannabis use disorders.
CBD continues to be studied for its effects on anxiety and depression symptoms. In fact, a study evaluating the potential usefulness of 150-300 mg of CBD per day for 12 weeks in people with bipolar disorder with anxiety and sadness will be completed in April 2022.
CBD may help alleviate some cancer-related symptoms and side effects associated with cancer therapy, such as nausea, vomiting, and pain. A study of the effects of CBD and THC in 177 people with cancer-related pain who had not responded to narcotic analgesics was conducted.
In an extract containing both chemicals, those who were treated experienced a greater reduction in pain than those who received only THC extract, according to a study. According to a review of five research papers, there is some evidence that Sativex can help with cancer-related pain in certain individuals.
However, the results of studies examining the effects of cannabis and cannabinoids like CBD on cancer-related nausea, pain, and loss of appetite have been conflicting.
Although CBD may be beneficial for some cancer patients, more study is needed to determine whether CBD should be used more often. If you have cancer and are interested in using CBD or other cannabis-derived products, it’s crucial that you talk to your doctor. These medicines may not work for everyone with cancer.
CBD’s ability to interact with the endocannabinoid system and other brain-signaling systems, according to experts, might help those with neurological disorders.
CBD has been investigated for a variety of medical applications, including treating neurological problems like epilepsy and MS. Although this subject is still relatively new, several studies have shown promising results. In people with MS, Sativex has been found to be both safe and effective in reducing muscular spasticity.
It helped reduce spasms in 75% of people with MS who were experiencing muscular spasticity that was resistant to drugs. In another study, researchers administered 2.0–5 grams of CBD oil per kg of body weight to 214 persons with severe epilepsy. The median reduction in seizures was 36.5 percent.
According to one more study, CBD oil reduced seizure activity in children with Dravet syndrome, a severe childhood epileptic condition, when compared to a placebo.
CBD, on the other hand, has been studied for its ability to treat a variety of neurological disorders. CBD has also been examined for its potential efficacy in treating various other neurological diseases.
CBD has been shown in several studies to benefit quality of life and sleep quality in Parkinson’s disease patients. However, researchers note that there is currently a scarcity of high-quality data. That implies there isn’t enough evidence to recommend CBD usage for clinical treatment of Parkinson’s disease at this time.
However, one CBD product has received FDA approval for use in the treatment of a variety of seizure disorders. Epidiolex, a prescription cannabidiol preparation, was authorized by the FDA in 2018 for the treatment of seizures associated with two serious types of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome.
Epidiolex was the first drug to be approved in the United States for treatment of tuberous sclerosis complex (TSC) seizures, a rare genetic disease that causes benign tumors to grow in the brain and other parts of the body.
CBD has been shown in studies to have beneficial effects on the heart and circulatory system, including the ability to lower high blood pressure. High blood pressure is linked to an increased risk of stroke, heart attack, and metabolic syndrome. CBD appears to be helpful for individuals with high blood pressure.
In a small study, 600 mg of CBD oil was given to 9 healthy men. The CBD treatment reduced resting blood pressure when compared with a placebo. Participants also took part in stress tests that typically cause blood pressure to rise. The single dose of CBD resulted in the participants’ having lower blood pressure increases than usual during the stressful situations. CBD reduced blood pressure in healthy men, according to one study. A 600 mg dose for 7 days was found to have significant reductions in blood pressure in the short term versus a placebo group, according to another research. However, after 7 days, the impact dissipated.
After multiple doses over time, the CBD group maintained lower blood pressure levels in response to stress than the placebo group. After repeated CBD dosing, the CBD group had reduced arterial stiffness and improved blood flow through their arteries, relative to the placebo group.
Overall, these findings are encouraging, but we need additional research on the potential benefits of CBD therapy in heart disease.
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